I've gotten to the point where I pretty much accept and work around the defaults and haven't really made an effort to cancel out all browser variations ... spend so much time with maintenance concerns that I tend to just go with what's worked in the past from times when I had ample time to do in-depth cross-browser, -platform testing.
I use Myer's reset on most sites. Also have built a few sites using blueprint. It is GREAT for mockups -- you can really quickly do a site mockup for design comps without spending time working out the browser kinks. Then - when you're ready to do your serious coding - you can either stick with blueprint - or convert your styles into your own CSS.
I've heard good things about 960gs - but haven't used it yet.
Found a list of CSS Frameworks, there are actually quite a lot out there. Some aim at resetting your browser's defaults, others are aimed at layouts, some come with PHP utlities (LogiCSS) while others attempt to redefine how you write CSS syntax entirely (CleverCSS).
I've looked at the YUI CSS Framework, 960 Grid System and Blueprint and found Blueprint to be the closest to what I want.
I've also found it great for sketching out designs quickly. There's nothing like a real web page for showing people what a particular web page design might look like.
@Michael McGlynn - as for complexity using Blueprint has made coding much easier/quicker for those in our team who aren't CSS gurus, and pretty much covers cross-browser compatibility out of the box.
I have used YUI Grids. I am trying BlueprintCSS on my next project. YUI Grids is nice if you are doing percentage based designs. I tend toward pixel perfect designs. I think BlueprintCSS will be better for pixel perfect designs.
I use 960 gs templates for designing but never really use the "framework", same with blueprint css. I do use the Myer's reset occasionally, but I have written my own reset before. I wouldn't really call these frameworks either. They are really rigid and do have limitations.
I would consider Compass and Sass to be true CSS frameworks that bring OOP to styling. Check it out.
I'm using BluePrint, it is awesome. There is also a site called constructyourcss.com which allows you to quickly add/edit/delete containers and columns. The 960 grid is good too. It doesn't do much with typography, but there is much more whitespace.
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